|
KMID : 0360120130350010038
|
|
Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
2013 Volume.35 No. 1 p.38 ~ p.50
|
|
|
Effect of Electron-beam Irradiaton on the Artificial Bone Substitutes Composed of Hydroxyapatite and Tricalcium Phosphate Mixtures with Type I Collagen
|
|
Park Jung-Min
Kim Soung-Min
Myoung Hoon
Lee Jong-Ho
Kim Min-Geun
Park Young-Wook
Lee Byung-Cheol
Lee Suk-Keun
|
|
|
Abstract
|
|
|
Purpose: The aim of this study is to evaluate the effect and potential of electron beam (E-beam) irradiation treatment to the synthetic bony mixtures composed of hydroxyapatite (HA; Bongros$^{(R)}$ 수식 이미지, Bio@ Co., Korea) and tricalcium phosphate (${\beta}$ 수식 이미지-TCP, Sigma-Aldrich Co., USA), mixed at various ratios and of type I collagen (Rat tail, BD Biosciences Co., Sweden) as an organic matrix.
Methods: We used 1.0~2.0 MeV linear accelerator and 2.0 MeV superconductive linear accelerator (power 100 KW, pressure 115 kPa, temperature $-30{\sim}120^{\circ}C$ 수식 이미지, sensor sensitivity 0.1~1.2 mV/kPa, generating power sensitivity 44.75 mV/kPa, supply voltage $5{\pm}0.25$ 수식 이미지 V) with different irradiation dose, such as 1, 30 and 60 kGy. Structural changes in this synthetic bone material were studied in vitro, by scanning electron microscopy (SEM), elementary analysis and field emission scanning electron microscope (FE-SEM), attenuated total reflection (ATR), and electron spectroscopy for chemical analysis (ESCA).
Results: The large particular size of HA was changed after E-beam irradiation, to which small particle of TCP was engaged with organic collagen components in SEM findings.
Conclusion:The important new in vitro data to be applicable as the substitutes of artificial bone materials in dental and medical fields will be able to be summarized.
|
|
|
KEYWORD
|
|
|
Bone regeneration, Hydroxyapatite, Tricalcium phosphate, Electron beam
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
 
|
|